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Breadcrumb Bioinformatics and Biostatistics Bioinformatics and Biostatistics : Publications Lab contentLab contentIn this section Overview Publications Members Bioinformatic visualisation of protein binding along a human chromosome, courtesy of Federico Agostini and Nick Luscombe. Toggle to view hero caption Publications Displaying 51 - 60 of 444Last updated : 18 April 2024 02:48 Lung adenocarcinoma promotion by air pollutants Authors (72)William HillEmilia LimClare Weeden Claudia Lee Marcellus Augustine Kezhong Chen[...] Kevin Litchfield TRACERx Consortium James DeGregori Mariam Jamal-HanjaniCharles Swanton Nature Published 6 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonIlaria MalanchiGeorge KassiotisJulian DownwardFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingLight MicroscopyBiological Research FacilityFull details Quantitative analysis of rabies virus-based synaptic connectivity tracing Authors (3)Alexandra Tran-Van-MinhZhiwen YeEde Rancz PLOS ONE Published 30 March 2023 Crick labs/ facilitiesEde RanczBioinformatics and BiostatisticsFull details Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation Authors (12)Oana PaunYu Xuan Tan Harshil Patel Stephanie StrohbueckerAvinash GhanateClementina Cobolli Gigli[...]Lina GerontogianniRobert GoldstoneSiew-Lan AngFrancois GuillemotCristina Dias Genes and Development Published 1 March 2023 Crick labs/ facilitiesFrancois GuillemotBioinformatics and BiostatisticsProteomicsLight MicroscopyHuman Embryonic Stem CellFlow CytometryAdvanced SequencingFull details The dietary sweetener sucralose is a negative modulator of T cell-mediated responses Authors (16)Fabio ZaniJulianna Blagih Tim GruberMichael Buck Nicholas JonesMarc Hennequart[...]Eric Cheung Ian S GilmoreAlex Gould Cristina Garcia-CaceresKaren Vousden Nature Published 23 March 2023 Crick labs/ facilitiesKaren VousdenCaetano Reis e SousaAlex GouldMetabolomicsBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details The CKS1/CKS2 proteostasis axis is crucial to maintain hematopoietic stem cell function Authors (11)William GreySamantha Atkinson Beatrice Rix Pedro CasadoLinda Ariza-Mcnaughton Cathy Hawley Miriam L Sopoena Katherine S Bridge David Kent Pedro R CutillasDominique Bonnet HemaSphere Published 1 March 2023 Crick labs/ facilitiesDominique BonnetBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityFull details Improved memory CD8 T cell response to delayed vaccine boost is associated with a distinct molecular signature Authors (16)Ambra Natalini Sonia Simonetti Gabriele Favaretto Lorenzo Lucantonio Giovanna PeruzziMiguel Munoz-Ruiz[...] Antonella Folgori Alfredo Nicosia Angela SantoniAdrian Hayday Francesca Di Rosa Frontiers in Immunology Published 14 February 2023 Crick labs/ facilitiesAdrian HaydayBioinformatics and BiostatisticsAdvanced SequencingFull details Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation Authors (8)Stefania Crotta Matteo VillaJack MajorKatja FinsterbuschMiriam Llorian Sopena Peter Carmeliet Joerg BuescherAndreas Wack Nature Communications Published 13 February 2023 Crick labs/ facilitiesAndreas WackBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details Cognitive impairments in a Down syndrome model with abnormal hippocampal and prefrontal dynamics and cytoarchitecture Authors (13) PM Muza D Bush M Pérez-González I Zouhair K Cleverley M Llorian-Sopena[...] M GoodVictor Tybulewicz MC Walker EMC Fisher P Chang iScience Published 17 February 2023 Crick labs/ facilitiesVictor TybulewiczBioinformatics and BiostatisticsFull details Systematic diet composition swap in a mouse genome-scale metabolic model reveals determinants of obesogenic diet metabolism in liver cancer Authors (7) Frederick ClasenPatricia Figueiredo Nunes Gholamreza Bidkhori Nourdine BahStefan Boeing Saeed ShoaieDimitrios Anastasiou iScience Published 17 February 2023 Crick labs/ facilitiesDimitrios AnastasiouBioinformatics and BiostatisticsMetabolomicsIn Vivo ImagingBiological Research FacilityAdvanced SequencingFull details B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice Authors (11)Darryl HaywardLesley Vanes Stefanie Wissmann Sujana Sivapatham Harald HartwegerJoshua Biggs O'MayLeon De Boer Richard MitterRobert Koechl Jens V SteinVictor Tybulewicz Journal of Experimental Medicine Published 6 March 2023 Crick labs/ facilitiesVictor TybulewiczBioinformatics and BiostatisticsMedia PreparationLight MicroscopyFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityFull details Pagination First page First Previous page Previous … Page 2 Page 3 Page 4 Page 5 Current page 6 Page 7 Page 8 Page 9 Page 10 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Lung adenocarcinoma promotion by air pollutants Authors (72)William HillEmilia LimClare Weeden Claudia Lee Marcellus Augustine Kezhong Chen[...] Kevin Litchfield TRACERx Consortium James DeGregori Mariam Jamal-HanjaniCharles Swanton Nature Published 6 April 2023 Crick labs/ facilitiesPeter Van LooCharles SwantonIlaria MalanchiGeorge KassiotisJulian DownwardFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingLight MicroscopyBiological Research FacilityFull details
Quantitative analysis of rabies virus-based synaptic connectivity tracing Authors (3)Alexandra Tran-Van-MinhZhiwen YeEde Rancz PLOS ONE Published 30 March 2023 Crick labs/ facilitiesEde RanczBioinformatics and BiostatisticsFull details
Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation Authors (12)Oana PaunYu Xuan Tan Harshil Patel Stephanie StrohbueckerAvinash GhanateClementina Cobolli Gigli[...]Lina GerontogianniRobert GoldstoneSiew-Lan AngFrancois GuillemotCristina Dias Genes and Development Published 1 March 2023 Crick labs/ facilitiesFrancois GuillemotBioinformatics and BiostatisticsProteomicsLight MicroscopyHuman Embryonic Stem CellFlow CytometryAdvanced SequencingFull details
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses Authors (16)Fabio ZaniJulianna Blagih Tim GruberMichael Buck Nicholas JonesMarc Hennequart[...]Eric Cheung Ian S GilmoreAlex Gould Cristina Garcia-CaceresKaren Vousden Nature Published 23 March 2023 Crick labs/ facilitiesKaren VousdenCaetano Reis e SousaAlex GouldMetabolomicsBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
The CKS1/CKS2 proteostasis axis is crucial to maintain hematopoietic stem cell function Authors (11)William GreySamantha Atkinson Beatrice Rix Pedro CasadoLinda Ariza-Mcnaughton Cathy Hawley Miriam L Sopoena Katherine S Bridge David Kent Pedro R CutillasDominique Bonnet HemaSphere Published 1 March 2023 Crick labs/ facilitiesDominique BonnetBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityFull details
Improved memory CD8 T cell response to delayed vaccine boost is associated with a distinct molecular signature Authors (16)Ambra Natalini Sonia Simonetti Gabriele Favaretto Lorenzo Lucantonio Giovanna PeruzziMiguel Munoz-Ruiz[...] Antonella Folgori Alfredo Nicosia Angela SantoniAdrian Hayday Francesca Di Rosa Frontiers in Immunology Published 14 February 2023 Crick labs/ facilitiesAdrian HaydayBioinformatics and BiostatisticsAdvanced SequencingFull details
Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation Authors (8)Stefania Crotta Matteo VillaJack MajorKatja FinsterbuschMiriam Llorian Sopena Peter Carmeliet Joerg BuescherAndreas Wack Nature Communications Published 13 February 2023 Crick labs/ facilitiesAndreas WackBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
Cognitive impairments in a Down syndrome model with abnormal hippocampal and prefrontal dynamics and cytoarchitecture Authors (13) PM Muza D Bush M Pérez-González I Zouhair K Cleverley M Llorian-Sopena[...] M GoodVictor Tybulewicz MC Walker EMC Fisher P Chang iScience Published 17 February 2023 Crick labs/ facilitiesVictor TybulewiczBioinformatics and BiostatisticsFull details
Systematic diet composition swap in a mouse genome-scale metabolic model reveals determinants of obesogenic diet metabolism in liver cancer Authors (7) Frederick ClasenPatricia Figueiredo Nunes Gholamreza Bidkhori Nourdine BahStefan Boeing Saeed ShoaieDimitrios Anastasiou iScience Published 17 February 2023 Crick labs/ facilitiesDimitrios AnastasiouBioinformatics and BiostatisticsMetabolomicsIn Vivo ImagingBiological Research FacilityAdvanced SequencingFull details
B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice Authors (11)Darryl HaywardLesley Vanes Stefanie Wissmann Sujana Sivapatham Harald HartwegerJoshua Biggs O'MayLeon De Boer Richard MitterRobert Koechl Jens V SteinVictor Tybulewicz Journal of Experimental Medicine Published 6 March 2023 Crick labs/ facilitiesVictor TybulewiczBioinformatics and BiostatisticsMedia PreparationLight MicroscopyFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityFull details