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Toggle to view hero caption Publications Displaying 41 - 50 of 133Last updated : 25 April 2024 03:23 Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation Authors (10)Rachel UlfertsElena Marcassa Lewis Timimi Liam Changwoo Lee Andrew DaleyBeatriz Montaner Suzanne Dawn Turner Oliver Florey John Kenneth BaillieRupert Beale Cell Reports Published 26 October 2021 Crick labs/ facilitiesRupert BealeLight MicroscopyFlow CytometryCell ServicesFull details Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry Authors (18)Febe VanMaldegemKarishma ValandMegan Cole Harshil PatelMihaela AngelovaSareena Rana[...]Philip HobsonDina LeviMiriam Molina ArcasCharles SwantonJulian Downward Nature Communications Published 8 October 2021 Crick labs/ facilitiesCharles SwantonJulian DownwardFlow CytometryBioinformatics and BiostatisticsScientific computingLight MicroscopyExperimental HistopathologyCell ServicesBiological Research FacilityFull details Gradual compaction of the central spindle decreases its dynamicity in PRC1 and EB1 gene-edited cells Authors (5)Jayant AsthanaNicholas Cade Davide Normanno Wei Ming Lim Thomas Surrey Life Science Alliance Published 1 December 2021 Crick labs/ facilitiesThomas SurreyFlow CytometryCell ServicesFull details PARP1 inhibitor combined with oxaliplatin efficiently suppresses oxaliplatin resistance in gastric cancer-derived organoids via homologous recombination and the base excision repair pathway Authors (15) Huafu Li Chunming WangLinxiang Lan Wenhui Wu Ian EvansJosue Ruiz[...] Zhenran Hu Wei ChenAxel Behrens Yulong He Changhua Zhang Frontiers in Cell and Developmental Biology Published 23 August 2021 Crick labs/ facilitiesAxel BehrensCell ServicesFull details Favourable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases Authors (31) Claire T Deakin Georgina H CornishKevin NgNikhil Faulkner William BollandJoshua Hope[...] Michael LevinPeter Cherepanov Coziana Ciurtin Lucy R WedderburnGeorge Kassiotis Med Published 10 September 2021 Crick labs/ facilitiesNeil McDonaldNicola LewisGeorge KassiotisSteve GamblinPeter Cherepanov Worldwide Influenza CentreFlow CytometryCell ServicesFull details Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains Authors (30)Nikhil FaulknerKevin NgMary Wu Ruth Harvey Marios Margaritis Stavroula Paraskevopoulou[...]Michael HowellDavid LV Bauer Eleni Nastouli SAFER InvestigatorsGeorge Kassiotis eLife Published 29 July 2021 Crick labs/ facilitiesCharles SwantonGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningFlow CytometryCell ServicesFull details An optogenetic method for interrogating YAP1 and TAZ nuclear-cytoplasmic shuttling Authors (11)Anna DowbajRob Jenkins Daniel Williamson John M HeddlestonAlessandro CiccarelliTodd Fallesen Klaus M Hahn Reuben D O'Dea John R King Marco MontagnerErik Sahai Journal of Cell Science Published 9 July 2021 Crick labs/ facilitiesErik SahaiLight MicroscopyFlow CytometryCell ServicesFull details E3 ubiquitin ligase HECTD2 mediates melanoma progression and immune evasion Authors (15)Eleonora OttinaVeera PanovaLaura DoglioAnastasiya Kazachenka Georgina CornishJoanna Kirkpatrick[...] Peter Van LooCharles SwantonJames Macrae Thomas TütingGeorge Kassiotis Oncogene Published 16 September 2021 Crick labs/ facilitiesPeter Van LooCharles SwantonJonathan StoyeGeorge KassiotisProteomicsMetabolomicsScientific computingLight MicroscopyFlow CytometryCell ServicesBiological Research FacilityFull details Translation stress and collided ribosomes are co-activators of cGAS Authors (11)Li Wan Szymon Juszkiewicz Daniel Blears Prashanth Kumar Bajpe Zhong HanPeter Faull Richard MitterAengus StewartBram Snijders Ramanujan S HegdeJesper Svejstrup Molecular Cell Published 1 July 2021 Crick labs/ facilitiesJesper SvejstrupProteomicsBioinformatics and BiostatisticsLight MicroscopyFlow CytometryCell ServicesAdvanced SequencingFull details An optogenetic method for interrogating YAP1 and TAZ nuclear-cytoplasmic shuttling Authors (11)Anna DowbajRob Jenkins Daniel Williamson John M HeddlestonAlessandro CiccarelliTodd Fallesen Klaus M Hahn Reuben D O'Dea John R King Marco MontagnerErik Sahai Journal of Cell Science Published 1 July 2021 Crick labs/ facilitiesErik SahaiLight MicroscopyFlow CytometryCell ServicesFull details Pagination First page First Previous page Previous Page 1 Page 2 Page 3 Page 4 Current page 5 Page 6 Page 7 Page 8 Page 9 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation Authors (10)Rachel UlfertsElena Marcassa Lewis Timimi Liam Changwoo Lee Andrew DaleyBeatriz Montaner Suzanne Dawn Turner Oliver Florey John Kenneth BaillieRupert Beale Cell Reports Published 26 October 2021 Crick labs/ facilitiesRupert BealeLight MicroscopyFlow CytometryCell ServicesFull details
Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry Authors (18)Febe VanMaldegemKarishma ValandMegan Cole Harshil PatelMihaela AngelovaSareena Rana[...]Philip HobsonDina LeviMiriam Molina ArcasCharles SwantonJulian Downward Nature Communications Published 8 October 2021 Crick labs/ facilitiesCharles SwantonJulian DownwardFlow CytometryBioinformatics and BiostatisticsScientific computingLight MicroscopyExperimental HistopathologyCell ServicesBiological Research FacilityFull details
Gradual compaction of the central spindle decreases its dynamicity in PRC1 and EB1 gene-edited cells Authors (5)Jayant AsthanaNicholas Cade Davide Normanno Wei Ming Lim Thomas Surrey Life Science Alliance Published 1 December 2021 Crick labs/ facilitiesThomas SurreyFlow CytometryCell ServicesFull details
PARP1 inhibitor combined with oxaliplatin efficiently suppresses oxaliplatin resistance in gastric cancer-derived organoids via homologous recombination and the base excision repair pathway Authors (15) Huafu Li Chunming WangLinxiang Lan Wenhui Wu Ian EvansJosue Ruiz[...] Zhenran Hu Wei ChenAxel Behrens Yulong He Changhua Zhang Frontiers in Cell and Developmental Biology Published 23 August 2021 Crick labs/ facilitiesAxel BehrensCell ServicesFull details
Favourable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases Authors (31) Claire T Deakin Georgina H CornishKevin NgNikhil Faulkner William BollandJoshua Hope[...] Michael LevinPeter Cherepanov Coziana Ciurtin Lucy R WedderburnGeorge Kassiotis Med Published 10 September 2021 Crick labs/ facilitiesNeil McDonaldNicola LewisGeorge KassiotisSteve GamblinPeter Cherepanov Worldwide Influenza CentreFlow CytometryCell ServicesFull details
Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains Authors (30)Nikhil FaulknerKevin NgMary Wu Ruth Harvey Marios Margaritis Stavroula Paraskevopoulou[...]Michael HowellDavid LV Bauer Eleni Nastouli SAFER InvestigatorsGeorge Kassiotis eLife Published 29 July 2021 Crick labs/ facilitiesCharles SwantonGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningFlow CytometryCell ServicesFull details
An optogenetic method for interrogating YAP1 and TAZ nuclear-cytoplasmic shuttling Authors (11)Anna DowbajRob Jenkins Daniel Williamson John M HeddlestonAlessandro CiccarelliTodd Fallesen Klaus M Hahn Reuben D O'Dea John R King Marco MontagnerErik Sahai Journal of Cell Science Published 9 July 2021 Crick labs/ facilitiesErik SahaiLight MicroscopyFlow CytometryCell ServicesFull details
E3 ubiquitin ligase HECTD2 mediates melanoma progression and immune evasion Authors (15)Eleonora OttinaVeera PanovaLaura DoglioAnastasiya Kazachenka Georgina CornishJoanna Kirkpatrick[...] Peter Van LooCharles SwantonJames Macrae Thomas TütingGeorge Kassiotis Oncogene Published 16 September 2021 Crick labs/ facilitiesPeter Van LooCharles SwantonJonathan StoyeGeorge KassiotisProteomicsMetabolomicsScientific computingLight MicroscopyFlow CytometryCell ServicesBiological Research FacilityFull details
Translation stress and collided ribosomes are co-activators of cGAS Authors (11)Li Wan Szymon Juszkiewicz Daniel Blears Prashanth Kumar Bajpe Zhong HanPeter Faull Richard MitterAengus StewartBram Snijders Ramanujan S HegdeJesper Svejstrup Molecular Cell Published 1 July 2021 Crick labs/ facilitiesJesper SvejstrupProteomicsBioinformatics and BiostatisticsLight MicroscopyFlow CytometryCell ServicesAdvanced SequencingFull details
An optogenetic method for interrogating YAP1 and TAZ nuclear-cytoplasmic shuttling Authors (11)Anna DowbajRob Jenkins Daniel Williamson John M HeddlestonAlessandro CiccarelliTodd Fallesen Klaus M Hahn Reuben D O'Dea John R King Marco MontagnerErik Sahai Journal of Cell Science Published 1 July 2021 Crick labs/ facilitiesErik SahaiLight MicroscopyFlow CytometryCell ServicesFull details
