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Breadcrumb Experimental Histopathology Experimental Histopathology : Publications Lab contentLab contentIn this section Overview Publications Members Publications Displaying 71 - 80 of 237Last updated : 23 April 2024 02:32 Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy Authors (23)Mylene TajanMarc HennequartEric CheungFabio Zani Andreas K HockNathalie Legrave[...] Adam Friedman Mark Manfredi Karen Blyth Owen J SansomKaren Vousden Nature Communications Published 14 January 2021 Crick labs/ facilitiesKaren VousdenVivian LiMetabolomicsExperimental HistopathologyBiological Research FacilityFull details Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth Authors (11)Rinako Nakagawa Amparo Toboso-Navasa Marta SchipsGeorge Young Leena Bhaw-RosunMiriam Llorian Sopena Probir Chakravarty Abdul Karim SesayGeorge Kassiotis Michael Meyer-HermannDinis Calado Proceedings of the National Academy of Sciences of USA Published 12 January 2021 Crick labs/ facilitiesGeorge KassiotisDinis CaladoBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityFull details Dentate gyrus development requires a cortical hem-derived astrocytic scaffold Authors (4)Alessia CaramelloChristophe GalichetKarine RizzotiRobin Lovell-Badge eLife Published 4 January 2021 Crick labs/ facilitiesRobin Lovell-BadgeLight MicroscopyExperimental HistopathologyBiological Research FacilityFull details CYP1A1 enzymatic activity influences skin inflammation via regulation of the AHR pathway Authors (14) Mariela KyorevaYing Li Mariyah Hoosenally Jonathan Hardman-Smart Kirsten Morrison Isabella Tosi[...] Ulrich Mrowietz Frank O Nestle Catherine Smith Jonathan N Barker Paola Di Meglio Journal of Investigative Dermatology Published 1 June 2021 Crick labs/ facilitiesGitta StockingerFlow CytometryExperimental HistopathologyBiological Research FacilityFull details Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells Authors (13)Syed Mian Ander Abarrategi Kar Lok KongKevin Rouault-Pierre Henry WoodCaroline Oedekoven[...]Linda Ariza-McnaughtonPeter JohnsonThomas Snoeks Ghulam J MuftiDominique Bonnet Blood Cancer Discovery Published 1 March 2021 Crick labs/ facilitiesDominique BonnetIn Vivo ImagingBiological Research FacilityFlow CytometryExperimental HistopathologyFull details Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells Authors (13)Syed Mian Ander Abarrategi Kar Lok KongKevin Rouault-Pierre Henry WoodCaroline Oedekoven[...]Linda Ariza-McnaughtonPeter JohnsonThomas Snoeks Ghulam J MuftiDominique Bonnet Blood Cancer Discovery Published 1 March 2021 Crick labs/ facilitiesDominique BonnetIn Vivo ImagingBiological Research FacilityFlow CytometryExperimental HistopathologyFull details Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD Authors (27) Graeme HewittValerie BorelSandra Segura-BayonaTohru TakakiPhil RuisRoberto Bellelli[...] Ivan Ahel Dragana Ahel J Ross Chapman Sebastian DeindlSimon Boulton Molecular Cell Published 18 February 2021 Crick labs/ facilitiesStephen WestSimon BoultonExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingGenetic Modification ServiceBiological Research FacilityFull details Generation of neighbor-labeling cells to study intercellular interactions in vivo Authors (10)Luigi OmbratoEmma NolanDiana Passaro Ivana KurelacVicky BridgemanAlexander Waclawiczek Delfim Duarte Cristina Lo CelsoDominique BonnetIlaria Malanchi Nature Protocols Published 1 February 2021 Crick labs/ facilitiesIlaria MalanchiDominique BonnetFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityFull details Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds Authors (22)Sara CampinotiAsllan GjinovciRoberta RagazziniLuca ZanieriLinda Ariza-Mcnaughton Marco Catucci[...] Sarah A Teichmann Neil J SebireAdrian HaydayDominique BonnetPaola Bonfanti Nature Communications Published 11 December 2020 Crick labs/ facilitiesAdrian HaydayDominique BonnetPaola BonfantiBioinformatics and BiostatisticsLight MicroscopyFlow CytometryExperimental HistopathologyElectron MicroscopyBiological Research FacilityAdvanced SequencingFull details Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH Authors (10)Hendrik MessalJorge Almagro May Zaw ThinAntonio TedeschiAlessandro Ciccarelli Laura BlackieKurt Anderson Irene Miguel-Aliaga Jacco van RheenenAxel Behrens Nature Protocols Published 1 January 2021 Crick labs/ facilitiesIrene Miguel-AliagaAxel BehrensLight MicroscopyExperimental HistopathologyBiological Research FacilityFull details Pagination First page First Previous page Previous … Page 4 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Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy Authors (23)Mylene TajanMarc HennequartEric CheungFabio Zani Andreas K HockNathalie Legrave[...] Adam Friedman Mark Manfredi Karen Blyth Owen J SansomKaren Vousden Nature Communications Published 14 January 2021 Crick labs/ facilitiesKaren VousdenVivian LiMetabolomicsExperimental HistopathologyBiological Research FacilityFull details
Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth Authors (11)Rinako Nakagawa Amparo Toboso-Navasa Marta SchipsGeorge Young Leena Bhaw-RosunMiriam Llorian Sopena Probir Chakravarty Abdul Karim SesayGeorge Kassiotis Michael Meyer-HermannDinis Calado Proceedings of the National Academy of Sciences of USA Published 12 January 2021 Crick labs/ facilitiesGeorge KassiotisDinis CaladoBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityFull details
Dentate gyrus development requires a cortical hem-derived astrocytic scaffold Authors (4)Alessia CaramelloChristophe GalichetKarine RizzotiRobin Lovell-Badge eLife Published 4 January 2021 Crick labs/ facilitiesRobin Lovell-BadgeLight MicroscopyExperimental HistopathologyBiological Research FacilityFull details
CYP1A1 enzymatic activity influences skin inflammation via regulation of the AHR pathway Authors (14) Mariela KyorevaYing Li Mariyah Hoosenally Jonathan Hardman-Smart Kirsten Morrison Isabella Tosi[...] Ulrich Mrowietz Frank O Nestle Catherine Smith Jonathan N Barker Paola Di Meglio Journal of Investigative Dermatology Published 1 June 2021 Crick labs/ facilitiesGitta StockingerFlow CytometryExperimental HistopathologyBiological Research FacilityFull details
Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells Authors (13)Syed Mian Ander Abarrategi Kar Lok KongKevin Rouault-Pierre Henry WoodCaroline Oedekoven[...]Linda Ariza-McnaughtonPeter JohnsonThomas Snoeks Ghulam J MuftiDominique Bonnet Blood Cancer Discovery Published 1 March 2021 Crick labs/ facilitiesDominique BonnetIn Vivo ImagingBiological Research FacilityFlow CytometryExperimental HistopathologyFull details
Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells Authors (13)Syed Mian Ander Abarrategi Kar Lok KongKevin Rouault-Pierre Henry WoodCaroline Oedekoven[...]Linda Ariza-McnaughtonPeter JohnsonThomas Snoeks Ghulam J MuftiDominique Bonnet Blood Cancer Discovery Published 1 March 2021 Crick labs/ facilitiesDominique BonnetIn Vivo ImagingBiological Research FacilityFlow CytometryExperimental HistopathologyFull details
Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD Authors (27) Graeme HewittValerie BorelSandra Segura-BayonaTohru TakakiPhil RuisRoberto Bellelli[...] Ivan Ahel Dragana Ahel J Ross Chapman Sebastian DeindlSimon Boulton Molecular Cell Published 18 February 2021 Crick labs/ facilitiesStephen WestSimon BoultonExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingGenetic Modification ServiceBiological Research FacilityFull details
Generation of neighbor-labeling cells to study intercellular interactions in vivo Authors (10)Luigi OmbratoEmma NolanDiana Passaro Ivana KurelacVicky BridgemanAlexander Waclawiczek Delfim Duarte Cristina Lo CelsoDominique BonnetIlaria Malanchi Nature Protocols Published 1 February 2021 Crick labs/ facilitiesIlaria MalanchiDominique BonnetFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityFull details
Reconstitution of a functional human thymus by postnatal stromal progenitor cells and natural whole-organ scaffolds Authors (22)Sara CampinotiAsllan GjinovciRoberta RagazziniLuca ZanieriLinda Ariza-Mcnaughton Marco Catucci[...] Sarah A Teichmann Neil J SebireAdrian HaydayDominique BonnetPaola Bonfanti Nature Communications Published 11 December 2020 Crick labs/ facilitiesAdrian HaydayDominique BonnetPaola BonfantiBioinformatics and BiostatisticsLight MicroscopyFlow CytometryExperimental HistopathologyElectron MicroscopyBiological Research FacilityAdvanced SequencingFull details
Antigen retrieval and clearing for whole-organ immunofluorescence by FLASH Authors (10)Hendrik MessalJorge Almagro May Zaw ThinAntonio TedeschiAlessandro Ciccarelli Laura BlackieKurt Anderson Irene Miguel-Aliaga Jacco van RheenenAxel Behrens Nature Protocols Published 1 January 2021 Crick labs/ facilitiesIrene Miguel-AliagaAxel BehrensLight MicroscopyExperimental HistopathologyBiological Research FacilityFull details