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Breadcrumb Proteomics Proteomics : Publications Lab contentLab contentIn this section Overview Publications Members The Mass Spectrometry Proteomics STP. Toggle to view hero caption Publications Displaying 1 - 10 of 209Last updated : 01 April 2023 03:57 Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation Authors (12)Oana PaunYu Xuan Tan Harshil Patel Stephanie StrohbueckerAvinash GhanateClementina Cobolli Gigli[...]Lina GerontogianniRobert GoldstoneSiew-Lan AngFrancois GuillemotCristina Dias Genes and Development Published 17 March 2023 Crick labs/ facilitiesFrancois GuillemotBioinformatics and BiostatisticsProteomicsLight MicroscopyHuman Embryonic Stem CellFlow CytometryAdvanced SequencingFull details O-linked sialoglycans modulate the proteolysis of SARS-CoV-2 spike and likely contribute to the mutational trajectory in variants of concern Authors (22)Edgar Gonzalez-RodriguezMia Zol-HanlonGanka Bineva-ToddAndrea MarchesiMark Skehel Keira E Mahoney[...]Robert Wilkinson Emma C Wall Ramón Hurtado-Guerrero Stacy A MalakerBen Schumann ACS Central Science Published 22 March 2023 Crick labs/ facilitiesRobert J WilkinsonBen SchumannSteve GamblinStructural BiologyProteomicsChemical BiologyFull details Profiling sulfur(VI) fluorides as reactive functionalities for chemical biology tools and expansion of the ligandable proteome Authors (11) Katharine E Gilbert Aini Vuorinen Arron Aatkar Peter Pogány Jonathan Pettinger Emma K GrantJoanna KirkpatrickKatrin Rittinger David House Glenn A Burley Jacob T Bush ACS Chemical Biology Published 17 February 2023 Crick labs/ facilitiesKatrin RittingerProteomicsFull details Bump-and-hole engineering of human polypeptide N-acetylgalactosamine transferases to dissect their protein substrates and glycosylation sites in cells Authors (10)Bea CalleEdgar Gonzalez-Rodriguez Keira E MahoneyAnna CioceGanka Bineva-ToddOmur Yilmaz TastanChloe Roustan Helen Flynn Stacy A MalakerBen Schumann STAR Protocols Published 17 March 2023 Crick labs/ facilitiesBen SchumannStructural BiologyProteomicsFull details Functional crosstalk between the cohesin loader and chromatin remodelers Authors (6)Sofia Munoz-FelixAndrew JonesCeline Bouchoux Tegan Gilmore Harshil PatelFrank Uhlmann Nature Communications Published 13 December 2022 Crick labs/ facilitiesFrank UhlmannProteomicsBioinformatics and BiostatisticsStructural BiologyPeptide ChemistryHigh Throughput ScreeningFermentationFull details Elongation factor-specific capture of RNA polymerase II complexes Authors (3) Lea H Gregersen Richard MitterJesper Svejstrup Cell Reports Methods Published 19 December 2022 Crick labs/ facilitiesJesper SvejstrupBioinformatics and BiostatisticsProteomicsAdvanced SequencingFull details Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restriction Authors (10)Simon ButterworthFrancesca TorelliEloise LockyerJeanette WagenerOk-Ryul SongMalgorzata (Malgorzata) BroncelMatt Russell Aline Cristina A Moreira-SouzaJoanna YoungMoritz Treeck PLOS Pathogens Published 7 December 2022 Crick labs/ facilitiesMoritz TreeckProteomicsHigh Throughput ScreeningElectron MicroscopyCell ServicesBiological Research FacilityAdvanced SequencingFull details Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration Authors (14) Flavia RoşianuSimeon MihaylovNoreen Eder Antonie MartiniucSuzanne Claxton Helen R Flynn[...]Mark SkehelBram Snijders Matthias KrauseSharon ToozeSila Ultanir Life Sci Alliance Published 1 February 2023 Crick labs/ facilitiesSila UltanirSharon ToozeProteomicsElectron MicroscopyExperimental HistopathologyFull details N6-methyladenosine (m6A) reader Pho92 is recruited co-transcriptionally and couples translation to mRNA decay to promote meiotic fitness in yeast Authors (18) Radhika A VarierTheodora SideriCharlotte CapitanchikZornitsa ManovaEnrica CalvaniAlice Rossi[...] Michiel VermeulenMarkus RalserJernej UleNicholas LuscombeFolkert Van Werven eLife Published 24 November 2022 Crick labs/ facilitiesFolkert van WervenJernej UleMarkus RalserNicholas LuscombeProteomicsMetabolomicsBioinformatics and BiostatisticsGenomics/Equipment ParkFermentationAdvanced SequencingFull details ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation Authors (15)Alexander Van VlietGeorge Chiduza Sarah L MaslenVal PyeDhira JoshiStefano De Tito[...]Javier Hervas HidalgoNicola O'ReillyMark SkehelPeter CherepanovSharon Tooze Molecular Cell Published 17 November 2022 Crick labs/ facilitiesSharon ToozePeter Cherepanov Structural BiologyProteomicsPeptide ChemistryLight MicroscopyElectron MicroscopyFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation Authors (12)Oana PaunYu Xuan Tan Harshil Patel Stephanie StrohbueckerAvinash GhanateClementina Cobolli Gigli[...]Lina GerontogianniRobert GoldstoneSiew-Lan AngFrancois GuillemotCristina Dias Genes and Development Published 17 March 2023 Crick labs/ facilitiesFrancois GuillemotBioinformatics and BiostatisticsProteomicsLight MicroscopyHuman Embryonic Stem CellFlow CytometryAdvanced SequencingFull details
O-linked sialoglycans modulate the proteolysis of SARS-CoV-2 spike and likely contribute to the mutational trajectory in variants of concern Authors (22)Edgar Gonzalez-RodriguezMia Zol-HanlonGanka Bineva-ToddAndrea MarchesiMark Skehel Keira E Mahoney[...]Robert Wilkinson Emma C Wall Ramón Hurtado-Guerrero Stacy A MalakerBen Schumann ACS Central Science Published 22 March 2023 Crick labs/ facilitiesRobert J WilkinsonBen SchumannSteve GamblinStructural BiologyProteomicsChemical BiologyFull details
Profiling sulfur(VI) fluorides as reactive functionalities for chemical biology tools and expansion of the ligandable proteome Authors (11) Katharine E Gilbert Aini Vuorinen Arron Aatkar Peter Pogány Jonathan Pettinger Emma K GrantJoanna KirkpatrickKatrin Rittinger David House Glenn A Burley Jacob T Bush ACS Chemical Biology Published 17 February 2023 Crick labs/ facilitiesKatrin RittingerProteomicsFull details
Bump-and-hole engineering of human polypeptide N-acetylgalactosamine transferases to dissect their protein substrates and glycosylation sites in cells Authors (10)Bea CalleEdgar Gonzalez-Rodriguez Keira E MahoneyAnna CioceGanka Bineva-ToddOmur Yilmaz TastanChloe Roustan Helen Flynn Stacy A MalakerBen Schumann STAR Protocols Published 17 March 2023 Crick labs/ facilitiesBen SchumannStructural BiologyProteomicsFull details
Functional crosstalk between the cohesin loader and chromatin remodelers Authors (6)Sofia Munoz-FelixAndrew JonesCeline Bouchoux Tegan Gilmore Harshil PatelFrank Uhlmann Nature Communications Published 13 December 2022 Crick labs/ facilitiesFrank UhlmannProteomicsBioinformatics and BiostatisticsStructural BiologyPeptide ChemistryHigh Throughput ScreeningFermentationFull details
Elongation factor-specific capture of RNA polymerase II complexes Authors (3) Lea H Gregersen Richard MitterJesper Svejstrup Cell Reports Methods Published 19 December 2022 Crick labs/ facilitiesJesper SvejstrupBioinformatics and BiostatisticsProteomicsAdvanced SequencingFull details
Toxoplasma gondii virulence factor ROP1 reduces parasite susceptibility to murine and human innate immune restriction Authors (10)Simon ButterworthFrancesca TorelliEloise LockyerJeanette WagenerOk-Ryul SongMalgorzata (Malgorzata) BroncelMatt Russell Aline Cristina A Moreira-SouzaJoanna YoungMoritz Treeck PLOS Pathogens Published 7 December 2022 Crick labs/ facilitiesMoritz TreeckProteomicsHigh Throughput ScreeningElectron MicroscopyCell ServicesBiological Research FacilityAdvanced SequencingFull details
Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration Authors (14) Flavia RoşianuSimeon MihaylovNoreen Eder Antonie MartiniucSuzanne Claxton Helen R Flynn[...]Mark SkehelBram Snijders Matthias KrauseSharon ToozeSila Ultanir Life Sci Alliance Published 1 February 2023 Crick labs/ facilitiesSila UltanirSharon ToozeProteomicsElectron MicroscopyExperimental HistopathologyFull details
N6-methyladenosine (m6A) reader Pho92 is recruited co-transcriptionally and couples translation to mRNA decay to promote meiotic fitness in yeast Authors (18) Radhika A VarierTheodora SideriCharlotte CapitanchikZornitsa ManovaEnrica CalvaniAlice Rossi[...] Michiel VermeulenMarkus RalserJernej UleNicholas LuscombeFolkert Van Werven eLife Published 24 November 2022 Crick labs/ facilitiesFolkert van WervenJernej UleMarkus RalserNicholas LuscombeProteomicsMetabolomicsBioinformatics and BiostatisticsGenomics/Equipment ParkFermentationAdvanced SequencingFull details
ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation Authors (15)Alexander Van VlietGeorge Chiduza Sarah L MaslenVal PyeDhira JoshiStefano De Tito[...]Javier Hervas HidalgoNicola O'ReillyMark SkehelPeter CherepanovSharon Tooze Molecular Cell Published 17 November 2022 Crick labs/ facilitiesSharon ToozePeter Cherepanov Structural BiologyProteomicsPeptide ChemistryLight MicroscopyElectron MicroscopyFull details
