Medicinal chemists at the Crick can offer guidance on best practice in chemical probe synthesis, selection, evaluation and use for testing a biological hypothesis.
If the best published small molecule tool for the planned experimental work is not commercially available, we can help you explore options for obtaining it, including synthesis.
Christelle Soudy offers extensive chemical knowledge and expertise in exploring SciFinder, Reaxys, PubChem and experience accessing MedchemExpress, Chemical Probes.org and Probe Miner.
Read more about Probeminer and other public resources for chemical probes in this 2019 special report in Future Medicinal Chemistry.
Read more about translation resources at the Crick.