We synthesise small molecules, such as enzyme inhibitors, modified nucleotides and cross-linking agents by solution phase chemistry techniques.
These are often useful in mass spectroscopy and structural studies and for modulating how proteins interact with each other. Projects can vary from one step to eight or nine steps as required.
Small molecules are purified and analysed using a range of techniques including mass spectroscopy, high-pressure liquid chromatography (HPLC), Nuclear Magnetic Resonance (NMR) and elemental analysis.
We are experts in chemistry and host Crick researchers in the chemistry space by providing synthesis expertise and safety supervision as well as fume hood space.