[2]Rotaxane formation by transition state stabilization
Abstract
We report on the synthesis of [2]rotaxanes driven by stabilization of the axle-forming transition state. A bifunctional macrocycle, with hydrogen bond donors at one end and acceptors at the other, is used to stabilize the charges that develop during the addition of a primary amine to a cyclic sulfate.
Journal details
Volume 139
Issue number 25
Pages 8455-8457
Available online
Publication date
Full text links
Publisher website (DOI) 10.1021/jacs.7b05640
Europe PubMed Central 28621939
Pubmed 28621939
Keywords
Type of publication