A comprehensive evaluation of rodent malaria parasite genomes and gene expression

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Abstract

Rodent malaria parasites (RMP) are used extensively as models of human malaria. Draft RMP genomes have been published for Plasmodium yoelii, P. berghei ANKA (PbA) and P. chabaudi AS (PcAS). Although availability of these genomes made a significant impact on recent malaria research, these genomes were highly fragmented and were annotated with little manual curation. The fragmented nature of the genomes has hampered genome wide analysis of Plasmodium gene regulation and function.

Journal details

Journal BMC Biology
Volume 12
Issue number 1
Pages 86
Publication date

Keywords