A comprehensive evaluation of rodent malaria parasite genomes and gene expressionMore about Open Access at the Crick
Authors listThomas D Otto Ulrike Böhme Andrew P Jackson Martin Hunt Blandine Franke-Fayard Wieteke AM Hoeijmakers Agnieszka A Religa Lauren Robertson Mandy Sanders Solabomi Ogun Deirdre Cunningham Annette Erhart Oliver Billker Shahid M Khan Hendrik G Stunnenberg Jean Langhorne Anthony Holder Andrew P Waters Chris I Newbold Arnab Pain Matthew Berriman Chris J Janse
Rodent malaria parasites (RMP) are used extensively as models of human malaria. Draft RMP genomes have been published for Plasmodium yoelii, P. berghei ANKA (PbA) and P. chabaudi AS (PcAS). Although availability of these genomes made a significant impact on recent malaria research, these genomes were highly fragmented and were annotated with little manual curation. The fragmented nature of the genomes has hampered genome wide analysis of Plasmodium gene regulation and function.