A mosaic variant in MAP2K1 is associated with giant naevus-spilus type congenital melanocytic naevus and melanoma development
More about Open Access at the CrickAbstract
Giant congenital melanocytic naevi (CMN) arise primarily due to postzygotic mutations in NRAS, and are of clinical importance due to their increased risk of malignant transformation.1 A subtype of large CMN, termed naevus spilus (NS)-type CMN, is identified by the presence of a patch which may have café-au-lait pigmentation and superimposed macular or papular lesions, which are demonstrably melanocytic naevi on histology.
Journal details
Journal British Journal of Dermatology
Volume 183
Issue number 4
Pages 760-761
Available online
Publication date
Full text links
Publisher website (DOI) 10.1111/bjd.19118
Figshare View on figshare
Europe PubMed Central 32271937
Pubmed 32271937
Keywords
Type of publication