A strong B-cell response is part of the immune landscape in human high-grade serous ovarian metastases

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In high-grade serous ovarian cancer (HGSOC), higher densities of both B cells and the CD8 T-cell infiltrate were associated with a better prognosis. However, the precise role of B cells in the antitumor response remains unknown. As peritoneal metastases are often responsible for relapse, our aim was to characterize the role of B cells in the antitumor immune response in HGSOC metastases.

Journal details

Volume 23
Issue number 1
Pages 250-262
Available online
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