AC/DC: Highway to cell
Abstract
Apoptotic cell (AC) corpses can be taken up by certain types of dendritic cell (DC), which cross-present dead cell-derived antigens. In this issue of JEM, Tam et al. (https://doi.org/10.1084/jem.20250887) reveal that GPR34, a lysophosphatidylserine receptor, promotes AC uptake and cross-presentation by type 1 DCs (cDC1s).
Journal details
Journal
Journal of Experimental Medicine
Volume
223
Issue number
1
Pages
e20251958
Available online
Publication date
Full text links
Publisher website (DOI)
10.1084/jem.20251958
Europe PubMed Central
41231226
Pubmed
41231226
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