Actin motility: formin a SCAry tail

Abstract

A new biochemical analysis has revealed that the Rickettsia bacterial protein Sca2--recently shown to be essential for virulence and actin-dependent motility--assembles actin filaments using a mechanism that functionally resembles the processive elongation tactics used by formins.

Journal details

Journal Current Biology
Volume 21
Issue number 1
Pages R27-R30
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