Actin'g against the ball and chain
Abstract
Spinocerebellar ataxia type 13 is a rare autosomal-dominant neurodegenerative disease induced by mutations in the voltage-dependent Kv3.3 potassium channel. Recently in Cell, Zhang et al. (2016) provide new insights into how Arp2/3-dependent actin polymerization modulates both Kv3.3 activity and its ability to stimulate actin polymerization via Hax-1.
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Publisher website (DOI) 10.1016/j.devcel.2016.03.014
Europe PubMed Central 27046828
Pubmed 27046828
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