Activation and transcriptional profile of monocytes and CD8+ T cells are altered in checkpoint inhibitor-related hepatitis

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Authors list

Cathrin LC Gudd Lewis Au Evangelos Triantafyllou Benjamin Shum Tong Liu Rooshi Nathwani Naveenta Kumar Sujit Mukherjee Ameet Dhar Kevin J Woollard You Yone David J Pinato Mark R Thursz Robert D Goldin Martin E Gore James Larkin Wafa Khamri Charalambos G Antoniades Samra Turajlic Lucia A Possamai
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Abstract

Checkpoint inhibitor-related hepatitis (CPI-Hep) is an emerging clinical challenge. We aimed to gain insights into the immunopathology of CPI-Hep by comprehensively characterising myeloid and lymphoid subsets.

Journal details

Journal Journal of hepatology
Volume 75
Issue number 1
Pages 177-189
Available online
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Publisher website (DOI) 10.1016/j.jhep.2021.02.008
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Europe PubMed Central 33631227
Pubmed 33631227

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