Advancing cancer biology: Highlights from the 2025 FASEB SRC on cellular plasticity in cancer

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Authors list

Hans Clevers Ankur Sharma Sendurai A Mani Anna Golebiewska Axel Behrens Wai Leong Tam Loic P Deleyrolle Huiping Liu Karuna Ganesh Walid T Khaled Shaheen Sikandar Terence K Lee Tyler E Miller Dean G Tang Sheila Singh Vivian Li Justin D Lathia Stephanie Ma
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Abstract

The inaugural FASEB Science Research Conference (SRC) on Cellular Plasticity in Cancer was held in May 2025 in Hong Kong SAR, China. This event brought together leading experts to discuss cutting-edge research centered on cancer cell plasticity. The conference featured comprehensive presentations covering a broad spectrum of topics, including oncofetal reprogramming in tumor development and progression, mechanisms regulating cancer cell plasticity, metabolic reprogramming and its role in tumor progression, cancer cell plasticity during metastasis, cancer stem cell programs within the tumor microenvironment, tumor plasticity and immune evasion, as well as innovative therapeutic strategies aimed at targeting stem cell-like states, modulating cancer cell states, and effectively controlling disease progression. It is anticipated that the insights gained from this meeting will catalyze further advancements in cancer biology and therapy.

Journal details

Journal Cancer Heterogeneity and Plasticity
Volume 2
Issue number 4
Pages 0018
Available online
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Publisher website (DOI) 10.47248/chp2502040018
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Europe PubMed Central 41221269
Pubmed 41221269

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