An ace model for SARS-CoV-2 infection
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Developing effective in vivo models for SARS-CoV-2 infection is crucial for mechanistic studies of COVID-19 disease progression. In this issue of JEM, Israelow et al. (https://doi.org/10.1084/jem.20201241) generate a model that supports SARS-CoV-2 infection in mice, which they use to characterize type I IFN-driven pulmonary inflammation.
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Journal Journal of Experimental Medicine
Volume 217
Issue number 12
Pages e20201748
Available online
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Publisher website (DOI) 10.1084/jem.20201748
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Europe PubMed Central 33000129
Pubmed 33000129
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