Author's overview: identifying SARS-CoV-2 antiviral compounds
More about Open Access at the CrickAbstract
In response to the COVID-19 pandemic, we began a project in March 2020 to identify small molecule inhibitors of SARS-CoV-2 enzymes from a library of chemical compounds containing many established pharmaceuticals. Our hope was that inhibitors we found might slow the replication of the SARS-CoV-2 virus in cells and ultimately be useful in the treatment of COVID-19. The seven accompanying manuscripts describe the results of these chemical screens. This overview summarises the main highlights from these screens and discusses the implications of our results and how our results might be exploited in future.
Journal details
Journal Biochemical Journal
Volume 478
Issue number 13
Pages 2533-2535
Available online
Publication date
Full text links
Publisher website (DOI) 10.1042/BCJ20210426
Figshare View on figshare
Europe PubMed Central 34198320
Pubmed 34198320
Keywords
Related topics
Type of publication