B cells producing type I IFN modulate macrophage polarization in tuberculosis

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Abstract

In addition to their well-known function as antibody-producing cells, B lymphocytes can markedly influence the course of infectious or noninfectious diseases via antibody-independent mechanisms. In tuberculosis (TB), B cells accumulate in lungs, yet their functional contribution to the host response remains poorly understood.

Journal details

Volume 197
Issue number 6
Pages 801-813
Available online
Publication date

Crick authors

Crick First author
Crick Corresponding author