Cancer screening, surrogates of survival, and the soma


Screening leads to meaningful reductions in deaths from cancers. However, reductions in all-cause mortality (ACM) are harder to demonstrate. Failure to demonstrate ACM benefit should not diminish advances in cancer screening. We consider how co-morbidities related to an aging and damaged soma can hinder achievement of ACM benefit.

Journal details

Journal Cancer Cell
Volume 38
Issue number 4
Pages 433-437
Available online
Publication date