Clone competition as a mechanism to reduce tumor formation
Abstract
With age, clones carrying somatic mutations in well-known cancer driver genes progressively populate adult tissues, yet cancer transformation is rare. In a recent issue of Nature, Colom et al. showed that competition between mutated clones with different fitness could act as a tumor-protective mechanism.
Journal details
Journal Developmental Cell
Volume 56
Issue number 24
Pages 3307-3308
Available online
Publication date
Full text links
Publisher website (DOI) 10.1016/j.devcel.2021.12.003
Europe PubMed Central 34932947
Pubmed 34932947
Keywords
Related topics
Type of publication