Computational methods for analysis of tumor clonality and evolutionary history
Abstract
Cancer is an evolutionary process. Recent advances in sequencing technologies have allowed us to investigate intratumor heterogeneity at the single nucleotide level. Here, we describe computational methods that use sequencing data to identify genetically distinct tumor subclones and reconstruct tumor evolutionary histories.
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Publisher website (DOI) 10.1007/978-1-4939-8868-6_13
Europe PubMed Central 30378079
Pubmed 30378079
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