Concentration-dependent antagonism and culture conversion in pulmonary tuberculosis

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Neesha Rockwood Jotam G Pasipanodya Paolo Denti Frederick Sirgel Maia Lesosky Tawanda Gumbo Graeme Meintjes Helen McIlleron Robert Wilkinson
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Abstract

There is scant evidence to support target drug exposures for optimal tuberculosis outcomes. We therefore assessed whether pharmacokinetic/pharmacodynamic (PK/PD) parameters could predict 2-month culture conversion.

Journal details

Journal Clinical Infectious Diseases
Volume 64
Issue number 10
Pages 1350-1359
Available online
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Publisher website (DOI) 10.1093/cid/cix158
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Europe PubMed Central 28205671
Pubmed 28205671

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