deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution
More about Open Access at the CrickAbstract
Analysis of somatic mutations provides insight into the mutational processes that have shaped the cancer genome, but such analysis currently requires large cohorts. We develop deconstructSigs, which allows the identification of mutational signatures within a single tumor sample.
Journal details
Journal Genome Biology
Volume 17
Issue number 1
Pages 31
Available online
Publication date
Full text links
Publisher website (DOI) 10.1186/s13059-016-0893-4
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Europe PubMed Central 26899170
Pubmed 26899170