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Let us introduce you to the fly breeders, laser guiders, cell growers, tech fixers and even bottle washers that make the science happen. Visit our free exhibition for an eye-opening glimpse of the people behind the science.
Exhibition entry: Free exhibition
Find out more about the key questions driving our research.
Discovery of 2-phenoxyacetamides as inhibitors of the Wnt-depalmitoleating enzyme NOTUM from an X-ray fragment screen
<p>Optimization of fragment hit <bold>3</bold> identified isoquinoline <bold>45</bold> as a potent inhibitor of NOTUM with an unexpected flipped binding mode.</p>