Flicking the Warburg switch-tyrosine phosphorylation of pyruvate dehydrogenase kinase regulates mitochondrial activity in cancer cells
Abstract
In this issue of Molecular Cell, Hitosugi et al. (2011) show that the switch from oxidative phosphorylation to glycolysis in cancer cells is regulated by tyrosine phosphorylation of PDHK1.
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Publisher website (DOI) 10.1016/j.molcel.2011.12.004
Europe PubMed Central 22195959
Pubmed 22195959
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