Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments

More about Open Access at the Crick


Enhanced macromolecule biosynthesis is integral to growth and proliferation of cancer cells. Lipid biosynthesis has been predicted to be an essential process in cancer cells. However, it is unclear which enzymes within this pathway offer the best selectivity for cancer cells and could be suitable therapeutic targets.

Journal details

Volume 4
Pages 6
Available online
Publication date