Interleukin-6 as a therapeutic target in human ovarian cancer

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Authors list

Jermaine Coward Hagen Kulbe Probir Chakravarty David Leader Vessela Vassileva D Andrew Leinster Richard Thompson Tiziana Schioppa Jeffery Nemeth Jessica Vermeulen Naveena Singh Norbert Avril Jeff Cummings Elton Rexhepaj Karin Jirstrom William M Gallagher Donal J Brennan Iain A McNeish Frances R Balkwill

Abstract

We investigated whether inhibition of interleukin 6 (IL-6) has therapeutic activity in ovarian cancer via abrogation of a tumor-promoting cytokine network.

Journal details

Journal Clinical cancer research
Volume 17
Issue number 18
Pages 6083-6096
Publication date

Full text links

Publisher website (DOI) 10.1158/1078-0432.ccr-11-0945
Europe PubMed Central 21795409
Pubmed 21795409

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