Investigation of influenza A(H5N1) virus neutralization by quadrivalent seasonal vaccines, United Kingdom, 2021–2024

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Phoebe Stevenson-Leggett Lorin Adams David Greenwood Abi Lofts Vincenzo Libri Bryan Williams Sonia Gandhi Charles Swanton Steve Gamblin Edward Carr Ruth Harvey Nicola Lewis Mary Wu Emma Wall
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Abstract

We tested cross-neutralization against highly pathogenic avian influenza A(H5N1) virus in adults vaccinated with 2021–2023 seasonal quadrivalent influenza vaccine in the United Kingdom. Seasonal quadrivalent influenza vaccines are unlikely to protect vulnerable persons against severe H5N1 disease during widespread transmission. Enhanced measures are needed to protect vulnerable people from H5N1 virus infection.

Journal details

Journal Emerging Infectious Diseases
Volume 31
Issue number 6
Pages 1202-1206
Available online
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Publisher website (DOI) 10.3201/eid3106.241796
Europe PubMed Central 40439507
Pubmed 40439507

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