IRaPPA: information retrieval based integration of biophysical models for protein assembly selection

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Abstract

In order to function, proteins frequently bind to one another and form 3D assemblies. Knowledge of the atomic details of these structures helps our understanding of how proteins work together, how mutations can lead to disease, and facilitates the designing of drugs which prevent or mimic the interaction.

Journal details

Journal Bioinformatics
Volume 33
Issue number 12
Pages 1806-1813
Available online
Publication date

Crick labs/facilities

Crick authors

Crick First author
Crick Corresponding author