ISSCR standards for the use of human stem cells in basic researchMore about Open Access at the Crick
Authors listTenneille E Ludwig Peter W Andrews Ivana Barbaric Nissim Benvenisty Anita Bhattacharyya Jeremy M Crook Laurence M Daheron Jonathan S Draper Lyn Healy Meritxell Huch Maneesha S Inamdar Kim B Jensen Andreas Kurtz Madeline A Lancaster Prisca Liberali Matthias P Lutolf Christine L Mummery Martin F Pera Yoji Sato Noriko Shimasaki Austin G Smith Jihwan Song Claudia Spits Glyn Stacey Christine A Wells Tongbiao Zhao Jack T Mosher
Toggle all authors (27)
The laboratory culture of human stem cells seeks to capture a cellular state as an in vitro surrogate of a biological system. For the results and outputs from this research to be accurate, meaningful, and durable, standards that ensure reproducibility and reliability of the data should be applied. Although such standards have been previously proposed for repositories and distribution centers, no widely accepted best practices exist for laboratory research with human pluripotent and tissue stem cells. To fill that void, the International Society for Stem Cell Research has developed a set of recommendations, including reporting criteria, for scientists in basic research laboratories. These criteria are designed to be technically and financially feasible and, when implemented, enhance the reproducibility and rigor of stem cell research.