Looping in on splicing: CRIC-seq uncovers PTBP1's long-range RNA regulatory rules


RNA looping adds crucial information to understanding the position-dependent regulatory mechanisms of protein-RNA interactions. In this issue, Xue et al.1 present CRIC-seq, which comprehensively identifies RNA loops mediated by specific proteins and demonstrates their value for interpreting disease-causing mutations.

Journal details

Journal Molecular Cell
Volume 83
Issue number 8
Pages 1206-1207
Available online
Publication date

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Crick First author
Crick Corresponding author