Making a choice: How cadherin switching controls cell migration
Abstract
Cells that undergo epithelial-to-mesenchymal transitions (EMTs) commonly switch from expressing E-cadherin to N-cadherin. But why this occurs is not well understood. In the current issue of Developmental Cell, Scarpa et al. (2015) identify a reason: cadherin switching controls Rac signaling to determine how cell locomotion is regulated by contact.
Journal details
Journal Developmental Cell
Volume 34
Issue number 4
Pages 383-384
Available online
Publication date
Full text links
Publisher website (DOI) 10.1016/j.devcel.2015.08.002
Europe PubMed Central 26305590
Pubmed 26305590
Keywords
Type of publication