Monocytes asphyxiate germinal centers


Some bacteria and parasites, such as Salmonella, actively disrupt germinal centers and elicit only low affinity antibodies, but the mechanisms by which microbes alter these responses is poorly understood. In this issue of Immunity, Biram et al. (2022) uncover a mechanism by which Salmonella recruits Sca-1+ monocytes to germinal centers and impairs metabolic adaptation.

Journal details

Journal Immunity
Volume 55
Issue number 3
Pages 385-387
Available online
Publication date