p73 keeps metabolic control in the family


The transcription factor p73, a close relative of p53, has complex yet poorly understood roles in tumorigenesis. TAp73, a p73 variant, has now been shown to promote cancer cell proliferation by regulating glucose metabolism to control cellular biosynthetic pathways and antioxidant capacity.

Journal details

Volume 15
Issue number 8
Pages 891-893
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Crick authors

Crick First author
Crick Corresponding author