p73 keeps metabolic control in the family
The transcription factor p73, a close relative of p53, has complex yet poorly understood roles in tumorigenesis. TAp73, a p73 variant, has now been shown to promote cancer cell proliferation by regulating glucose metabolism to control cellular biosynthetic pathways and antioxidant capacity.
Journal Nature Cell Biology
Issue number 8
Full text links
Publisher website (DOI) 10.1038/ncb2810
Europe PubMed Central 23907193
Type of publication