Plasmodium peekaboo: PK4 mediates parasite latency
Abstract
In this issue of Cell Host & Microbe, Zhang et al. (2017) show that translational repression through eIF2α phosphorylation mediated by PK4 kinase activity plays a key role in artemisinin resistance in recrudescent malaria infections. Targeting this druggable process could extend the lifespan of current frontline treatments.
Full text links
Publisher website (DOI) 10.1016/j.chom.2017.11.011
Europe PubMed Central 29241036
Pubmed 29241036
Keywords
Related topics
Type of publication
