Prolonged tuberculosis-associated immune reconstitution inflammatory syndrome: characteristics and risk factors
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Tasnim M Bana Maia Lesosky Dominique J Pepper Helen van der Plas Charlotte Schutz Rene Goliath Chelsea Morroni Marc Mendelson Gary Maartens Robert Wilkinson Graeme MeintjesAbstract
In a proportion of patients with HIV-associated tuberculosis who develop paradoxical immune reconstitution inflammatory syndrome (IRIS), the clinical course of IRIS is prolonged necessitating substantial health care utilization for diagnostic and therapeutic interventions. Prolonged TB-IRIS has not been prospectively studied to date. We aimed to determine the proportion of patients with prolonged TB-IRIS, as well as the clinical characteristics and risk factors for prolonged TB-IRIS.
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Journal BMC Infectious Diseases
Volume 16
Issue number 1
Pages 518
Available online
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Publisher website (DOI) 10.1186/s12879-016-1850-2
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Europe PubMed Central 27677424
Pubmed 27677424
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