Quantification of biomarker functionality predicts patient outcomes

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Abstract

Implementation of a quantitative molecular imaging method (iFRET), which determines receptor-ligand interactions, has led to the finding that patients with a low extent of PD-1/PD-L1 interaction in metastatic NSCLC, and malignant melanoma, display significantly worsened overall survival compared to those with a high level of interaction.

Journal details

Volume 124
Issue number 10
Pages 1618-1620
Available online
Publication date

Crick labs/facilities