Recent progress in understanding immune activation in the pathogenesis in HIV-tuberculosis co-infection

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Elsa du Bruyn Nashied Peton Hanif Esmail Patrick J Howlett Anna K Coussens Robert Wilkinson
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Abstract

Tuberculosis is the leading infectious cause of death worldwide, and HIV-1 the best recognized risk factor for active TB. This review focuses on immune complex formation; the interplay of type I and II interferon signaling; and T-cell activation in HIV-TB pathogenesis.

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Journal Current Opinion in HIV and AIDS
Volume 13
Issue number 6
Pages 455-461
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Publisher website (DOI) 10.1097/coh.0000000000000501
Europe PubMed Central 30286038
Pubmed 30286038

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