Repeated clinical malaria episodes are associated with modification of the immune system in children

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Abstract

There are over 200 million reported cases of malaria each year, and most children living in endemic areas will experience multiple episodes of clinical disease before puberty. We set out to understand how frequent clinical malaria, which elicits a strong inflammatory response, affects the immune system and whether these modifications are observable in the absence of detectable parasitaemia.

Journal details

Journal BMC Medicine
Volume 17
Issue number 1
Pages 60-60
Publication date

Crick authors

Crick First author
Crick Corresponding author