Risk factors for acquired rifamycin and isoniazid resistance: a systematic review and meta-analysis

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Studies looking at acquired drug resistance (ADR) are diverse with respect to geographical distribution, HIV co-infection rates, retreatment status and programmatic factors such as regimens administered and directly observed therapy. Our objective was to examine and consolidate evidence from clinical studies of the multifactorial aetiology of acquired rifamycin and/or isoniazid resistance within the scope of a single systematic review. This is important to inform policy and identify key areas for further studies.

Journal details

Journal PLOS ONE
Volume 10
Issue number 9
Pages e0139017
Available online
Publication date

Crick authors

Crick First author
Crick Corresponding author