Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer

Authors list

Mary Wu Scott Shepherd Annika Fendler Edward J Carr Lewis Au Ruth Harvey Giulia Dowgier Agnieszka Hobbs Lou S Herman Martina Ragno Lorin Adams Andreas M Schmitt Zayd Tippu Benjamin Shum Sheima Farag Aljosja Rogiers Nicola O'Reilly Philip Bawumia Callie Smith Eleanor Carlyle Kim Edmonds Lyra Del Rosario Karla Lingard Mary Mangwende Lucy Holt Hamid Ahmod Justine Korteweg Tara Foley Taja Barber Stephanie Hepworth Andrea Emslie-Henry Niamh Caulfield-Lynch Fiona Byrne Daqi Deng Bryan Williams Michael Brown Simon Caidan Mike Gavrielides James Macrae Gavin Kelly Kema Peat Denise Kelly Aida Murra Kayleigh Kelly Molly O'Flaherty Sanjay Popat Nadia Yousaf Shaman Jhanji Kate Tatham David Cunningham Nicholas Van As Kate Young Andrew JS Furness Lisa Pickering Rupert Beale Charles Swanton Sonia Gandhi Steve Gamblin David LV Bauer George Kassiotis Michael Howell Susanna Walker Emma Nicholson James Larkin Emma C Wall Samra Turajlic CAPTURE consortium
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Abstract

Wu et al. report that patients with hematologic malignancies have reduced immunity against SARS-CoV-2 Omicron subvariants and Sotrovimab retains neutralizing capacity against all tested Omicron subvariants.

Journal details

Journal Cancer Cell
Volume 41
Issue number 5
Pages 821-823
Available online
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Publisher website (DOI) 10.1016/j.ccell.2023.04.005
Europe PubMed Central 37116490
Pubmed 37116490

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