Steering cell migration by alternating blebs and actin-rich protrusions

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Abstract

High directional persistence is often assumed to enhance the efficiency of chemotactic migration. Yet, cells in vivo usually display meandering trajectories with relatively low directional persistence, and the control and function of directional persistence during cell migration in three-dimensional environments are poorly understood.

Journal details

Journal BMC Biology
Volume 14
Pages 74
Available online
Publication date

Crick labs/facilities

Crick authors

Crick First author
Crick Corresponding author