Supplementary Tables S1-S8 from Late-stage metastatic melanoma emerges through a diversity of evolutionary pathways
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Lavina Spain Alex Coulton Irene Lobon Andrew Rowan Desiree Schnidrig Scott Shepherd Benjamin Shum Fiona Byrne Maria Goicoechea Lewis Au Charlotte Spencer Andreas M Schmitt Zayd Tippu Anne-Laure Cattin Max Emmerich Camille L Gerard Husayn Pallikonda Aljosja Rogiers Hang Xu Ariana Huebner Nicholas McGranahan Maise Al Bakir Cristina Naceur-Lombardelli David A Moore Gordon WH Stamp Emma Nye Kevin Litchfield Charles Swanton Mariam Jamal-Hanjani Samra Turajlic
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Abstract
S. Table 1: List of PEACE Consortium members.
S. Table 2: Sample database used for the study for Panel, Exome and RNASeq samples.
S. Table 3: Overview of lines of treatment given to each patient.
S. Table 4: Lesions and patients included in the lesion-level response to ICI analysis.
S. Table 5: Hallmark genesets significantly upregulated in normal tissue vs tumor tissue. Table shows p-values for tissue type, purity; T value for tissue type, purity; q-value for tissue type, purity (FDR corrected).
S. Table 6: Hallmark genesets significantly upregulated in tumor tissue vs normal tissue. Table shows p-values for tissue type, purity; T value for tissue type, purity; q-value for tissue type, purity (FDR corrected).
S. Table 7: Genes included in the target panel.
S. Table 8: Tree topology comparisons between manually constructed trees and pairtree-constructed trees.</p>
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