The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognitionMore about Open Access at the Crick
Authors listGareth Prosser Brandenburg Julius Norbert Reiling Clifton Earl Barry Robert Wilkinson Katalin Wilkinson
Mycobacterium tuberculosis is a facultative anaerobe and its characteristic pathological hallmark, the granuloma, exhibits hypoxia in humans and in most experimental models. Thus the host and bacillary adaptation to hypoxia is of central importance in understanding pathogenesis and thereby to derive new drug treatments and vaccines.
Journal Microbes and Infection
Issue number 3