The European Hematology Association Roadmap for European Hematology Research: a consensus document
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Andreas Engert Carlo Balduini Anneke Brand Bertrand Coiffier Catherine Cordonnier Hartmut Döhner Thom Duyvené de Wit Sabine Eichinger Willem Fibbe Tony Green Fleur de Haas Achille Iolascon Thierry Jaffredo Francesco Rodeghiero Gilles Salles Jan Jacob Schuringa Marc André Isabelle Andre-Schmutz Andrea Bacigalupo Pierre-Yves Bochud Monique den Boer Chiara Bonini Clara Camaschella Andrew Cant Maria Domenica Cappellini Mario Cazzola Cristina Lo Celso Meletios Dimopoulos Luc Douay Elaine Dzierzak Hermann Einsele Andrés Ferreri Lucia De Franceschi Philippe Gaulard Berthold Gottgens Andreas Greinacher Paolo Gresele John Gribben Gerald de Haan John-Bjarne Hansen Andreas Hochhaus Rezan Kadir Srini Kaveri Valerie Kouskoff Thomas Kühne Paul Kyrle Per Ljungman Georg Maschmeyer Simón Méndez-Ferrer Michael Milsom Christine Mummery Gert Ossenkoppele Alessandro Pecci Flora Peyvandi Sjaak Philipsen Pieter Reitsma José Maria Ribera Antonio Risitano Stefano Rivella Wolfram Ruf Timm Schroeder Marie Scully Gerard Socie Frank Staal Simon Stanworth Reinhard Stauder Stephan Stilgenbauer Hannah Tamary Kim Theilgaard-Mönch Swee Lay Thein Hervé Tilly Marek Trneny William Vainchenker Alessandro Maria Vannucchi Claudio Viscoli Hans Vrielink Hans Zaaijer Alberto Zanella Lello Zolla Jaap Jan Zwaginga Patricia Aguilar Martinez Emile van den Akker Shubha Allard Nicholas Anagnou Immacolata Andolfo Jean Christophe Andrau Emanuele Angelucci David Anstee Igor Aurer Hervé Avet-Loiseau Yesim Aydinok Tamam Bakchoul Alessandra Balduini Wilma Barcellini Dominique Baruch André Baruchel Jagadeesh Bayry Celeste Bento Anke van den Berg Rosa Bernardi Paola Bianchi Anna Bigas Andrea Biondi Milos Bohonek Dominique Bonnet Peter Borchmann Niels Borregaard Sigrid Brækkan Marcel van den Brink Ellen Brodin Lars Bullinger Christian Buske Barbara Butzeck Jörg Cammenga Elias Campo Antonino Carbone Francisco Cervantes Simone Cesaro Pierre Charbord Frans Claas Hannah Cohen Jacqueline Conard Paul Coppo Joan-Lluis Vives Corrons Lydie da Costa Frederic Davi Ruud Delwel Irma Dianzani Dragoslav Domanović Peter Donnelly Tadeja DovčDrnovšek Martin Dreyling Ming-Qing Du Carlo Dufour Charles Durand Dimitar Efremov Androulla Eleftheriou Jacques Elion Marieke Emonts Monika Engelhardt Sophie Ezine Fred Falkenburg Remi Favier Massimo Federico Pierre Fenaux Jude Fitzgibbon Johan Flygare Robin Foà Lesley Forrester Frederic Galacteros Isabella Garagiola Chris Gardiner Olivier Garaud Christel van Geet Hartmut Geiger Jan Geissler Ulrich Germing Cedric Ghevaert Domenico Girelli Bertrand Godeau Nicola Gökbuget Hartmut Goldschmidt Anne Goodeve Thomas Graf Giovanna Graziadei Martin Griesshammer Yves Gruel Francois Guilhot Stephan von Gunten Inge Gyssens Jörg Halter Claire Harrison Cornelis Harteveld Eva Hellström-Lindberg Olivier Hermine Douglas Higgs Peter Hillmen Hans Hirsch Peter Hoskin Gerwin Huls Adlette Inati Peter Johnson Antonis Kattamis Volker Kiefel Marina Kleanthous Hannes Klump Daniela Krause Johanna Kremer Hovinga Georg Lacaud Sébastien Lacroix-Desmazes Judith Landman-Parker Steven LeGouill Georg Lenz Marie von Lilienfeld-Toal Marieke von Lindern Armando Lopez-Guillermo Enrico Lopriore Miguel Lozano Elizabeth MacIntyre Michael Makris Christine Mannhalter Joost Martens Stephan Mathas Axel Matzdorff Alexander Medvinsky Pablo Menendez Anna Rita Migliacco Kenichi Miharada Malgorzata Mikulska Véronique Minard Carlos Montalbán Mariane de Montalambert Emili Montserrat Pierre Emmanuel Morange Joanne Mountford Martina Muckenthaler Carsten Müller-Tidow Andrew Mumford Bertrand Nadel Jose-Tomas Navarro Wassim el Nemer France Noizat-Pirenne Brain O'Mahony Johannes Oldenburg Marianne Olsson Robert Oostendorp Antonio Palumbo Francesco Passamonti Roger Patient Regis Peffault de Latour Francoise Pflumio Luca Pierelli Antonio Piga Debra Pollard Marc Raaijmakers John Radford Ralf Rambach A Koneti Rao Hana Raslova Paola Rebulla David Rees Vincent Ribrag Anita Rijneveld Sara Rinalducci Tadeusz Robak Irene Roberts Charlene Rodrigues Frits Rosendaal Andreas Rosenwald Simon Rule Roberta Russo Giuseppe Saglio Mayka Sanchez Rüdiger E Scharf Peter Schlenke John Semple Jorge Sierra Cynthia So-Osman José Manuel Soria Kostas Stamatopoulos Bernd Stagmayr Henk Stunnenberg Dorine Swinkels João Pedro Taborda Barata Tom Taghon Ali Taher Evangelos Terpos Jecko Thachil Jean Daniel Tissot Ivo Touw Ash Toye Ralf Trappe Alexandra Traverse-Glehen Sule Unal Sophie Vaulont Vip Viprakasit Umberto Vitolo Richard van Wijck Agnieszka Wójtowicz Sacha Zeerleder Barbara Zieger Toggle all authors (281)
Abstract
The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap.The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders.The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients.
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Publisher website (DOI) 10.3324/haematol.2015.136739
Europe PubMed Central 26819058
Pubmed 26819058
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