The extracellular matrix viscoelasticity as a regulator of cell and tissue dynamics
Abstract
The extracellular matrix mechanical properties regulate processes in development, cancer, and fibrosis. Among the distinct mechanical properties, the vast majority of research has focused on the extracellular matrix's elasticity as the primary determinant of cell and tissue behavior. However, both cells and the extracellular matrix are not only elastic but also viscous. Despite viscoelasticity being a universal feature of living tissues, our knowledge of the influence of the extracellular matrix's viscoelasticity in cell behavior is limited. This mini-review describes some of the recent findings that have highlighted the role of the extracellular matrix's viscoelasticity in cell and tissue dynamics.
Journal details
Journal Current Opinion in Cell Biology
Volume 72
Pages 10-18
Available online
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Publisher website (DOI) 10.1016/j.ceb.2021.04.002
Europe PubMed Central 33993058
Pubmed 33993058
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