The innate immune response in human tuberculosis
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Mycobacterium tuberculosis (Mtb) infection can be cleared by the innate immune system before the initiation of an adaptive immune response. This innate protection requires a variety of robust cell autonomous responses from many different host immune cell types. However, Mtb has evolved strategies to circumvent some of these defences. In this mini-review, we discuss these host-pathogen interactions with a focus on studies performed in human cells and/or supported by human genetics studies (such as genome-wide association studies).
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Journal Cellular Microbiology
Volume 17
Issue number 9
Pages 1277-1285
Available online
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Publisher website (DOI) 10.1111/cmi.12480
Europe PubMed Central 26135005
Pubmed 26135005
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