The intracellular plasma membrane-connected compartment in the assembly of HIV-1 in human macrophages
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In HIV-infected macrophages, newly formed progeny virus particles accumulate in intracellular plasma membrane-connected compartments (IPMCs). Although the virus is usually seen in these compartments, it is unclear whether HIV assembly is specifically targeted to IPMCs or whether some viruses may also form at the cell surface but are not detected, as particles budding from the latter site will be released into the medium.
Journal details
Journal BMC Biology
Volume 14
Issue number 1
Pages 50
Available online
Publication date
Full text links
Publisher website (DOI) 10.1186/s12915-016-0272-3
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Europe PubMed Central 27338237
Pubmed 27338237