The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcomeMore about Open Access at the Crick
The advent of rapid and inexpensive sequencing technology allows scientists to decipher heterogeneity within primary tumours, between primary and metastatic sites, and between metastases. Charting the evolutionary history of individual tumours has revealed drivers of tumour heterogeneity and highlighted its impact on therapeutic outcomes.
Journal BMC Medicine
Issue number 1