The zinc finger transcription factor PW1/PEG3 restrains murine beta cell cycling
Authors listMozhdeh Sojoodi Leslie Stradiot Karo Tanaka Yves Heremans Gunter Leuckx Vanessa Besson Willem Staels Mark Van de Casteele Giovanna Marazzi David Sassoon Harry Heimberg Paola Bonfanti
Pw1 or paternally-expressed gene 3 (Peg3) encodes a zinc finger transcription factor that is widely expressed during mouse embryonic development and later restricted to multiple somatic stem cell lineages in the adult. The aim of the present study was to define Pw1 expression in the embryonic and adult pancreas and investigate its role in the beta cell cycle in Pw1 wild-type and mutant mice.
Issue number 7
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Publisher website (DOI) 10.1007/s00125-016-3954-z
Europe PubMed Central 27130279
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